“Death is optional.” — Yuval Noah Harari
The key to immortality is evolving beyond death. That means first treating it as a possible and optional outcome, instead of an inevitability. This could be a powerful step that causes physiological, intellectual and emotional change, like meditation alters brain chemistry. The mere fact that this concept is circulating indicates possibility.
Consider all the technologies borrowed from sci-fi that have come into being, with more on the horizon. For those who do or don’t want to live forever, that’s a choice. And choice is how species branch off. All organisms change, yet some at faster rates and choosing different directions.
Evolution, or growth, is and has been always alive and in motion. All levels of organisms on all scales of life have made choices in some way or another to get to where we are now. Even then, choices are still as malleable as the stem cells of the human body.
Death started occurring when Multicellular organisms developed, an estimated 600 million years ago.¹ Programmed cell death or “PCD” became advantageous as a way to correct course or errors. That was just part of the beginning of group behavior, when bunches of cells got together to build something greater than themselves. And Intelligence has been growing ever since.
Now here we are, the lot of us, from subatomic origins to elaborate systems — Humans are complex, increasingly self aware and knowledgeable multicellular organisms, able to make many conscious course corrections within a single lifetime. And those choices, such as change of environment, or detox of environment, affect our DNA.
The Mitochondria of our cells, and there can be up to tens of thousands in each cell, have been involved with “apoptosis,” yet another term for programmed cell death, along with signaling proteins called cytokines.
One research article I found humorously describes apoptosis with this headline: “Mitochondria have been accused of murder.”
Apoptosis occurs, in part, because of Ca2+ or calcium ion overload, Ca2+ being an important intracellular regulator.³ What does that mean?
Calcium ions “play an important role in signal transduction pathways, where they act as a second messenger, in neurotransmitter release from neurons, in contraction of all muscle cell types, and in fertilization. Many enzymes require calcium ions as a cofactor, including several of the coagulation factors. Extracellular calcium is also important for maintaining the potential difference across excitable cell membranes, as well as proper bone formation.”⁴
It can be useful to take a multidisciplinary approach, cross referencing engineering, electronics and music to understand. A transducer converts energy or signal from one type to another. Transducer overload occurs when the incoming voltage is higher than the sensor can handle.⁵
The implication within the human cell, is that preventing mismatch and overload of unstable atoms is the answer. After all, “an ounce of prevention is worth a pound of cure.”
Very generally, efficient sharing of electrons is the answer. And what helps increase this intracellular intelligence? Reportedly, physically reconnecting with the Earth’s surface electrons,⁶ and deep breathing. Connect to Earth — connect to ourselves. Deep learn ourselves — evolve.
Let’s be fair though — it’s a complex symphony in there. Not just any orchestra gets Gustav Mahler exactly right. If a instrumentalist misses a note, for example, they just have to keep going. This is example is comparing of course a biochemical chain reaction to a musical piece performed on a stage. In a grand auditorium, in most cases, there’s no starting over — you just have to get it right, or mostly right, and keep moving forward.
The cellular symphony is a bit more flexible though, simultaneously operating on atomic and quantum subatomic levels. And that’s how a molecule like “Pseudouridine” comes in handy. Pseudouridine (Ψ) is an RNA editor and stabilizer, and a key ingredient of Covid-19 mRNA vaccines, modified and unmodified. It has also exhibited anti-apoptotic effects.⁷
1. How Did Multicellular Life Evolve? | Charles Q. Choi 2017 | https://astrobiology.nasa.gov/news/how-did-multicellular-life-evolve/
2. Apoptosis: Mitochondria Accused of Murder | https://www.rndsystems.com/resources/articles/apoptosis-mitochondria-accused-murder
3. The calcium ion and cell death | S Orrenius, P Nicotera | https://pubmed.ncbi.nlm.nih.gov/7884392/
4. Calcium In Biology | https://en.wikipedia.org/wiki/Calcium_in_biology
5. Overloads | https://community.sw.siemens.com/s/article/overloads
6. Earthing: Health Implications of Reconnecting the Human Body to the Earth’s Surface Electrons | Gaétan Chevalier, Stephen T. Sinatra, […], and Pawel Sokal | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265077/
7. The Critical Contribution of Pseudouridine to mRNA COVID-19 Vaccines | Pedro Morais, Hironori Adachi and Yi-Tao Yu | https://www.frontiersin.org/articles/10.3389/fcell.2021.789427/full